The antidepressant effects were also assessed using the forced swim test and the open field test. The present study investigated the antianxiety effects of LMT in rats using the elevated plus maze and the hot plate test. LMT has also been reported to have antidepressant effects in mice and rodents. Lomitapide (LMT), an inhibitor of the apolipoprotein (apo) C-III converting enzyme, has been reported to decrease very low density lipoprotein (VLDL) and low density lipoprotein (LDL) metabolism in humans.

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